Fig. 2

Levels of aPL subtypes determined by ELISA. The aPL subtypes in canine sera were measured. Group I: outpatient dogs with thrombocytopenia (n = 64). Subgroups of Group I: I_A (n = 20) (immune thrombocytopenia, aPLT⁺, platelet count < 30 × 10³/uL), I_B (n = 18) (severe thrombocytopenia, aPLT^-, platelet count < 30 × 10³/uL), and I_C (n = 26) (less severe thrombocytopenia, platelet count 30 – 80 × 10³/uL). Group II: outpatient dogs without thrombocytopenia (n = 30). Group III: healthy dogs (n = 80). ^*Group I, or subgroup I_A, I_B, or I_C is significantly higher than Group II (^*** P < 0.001, ^** P < 0.01, ^* P < 0.05). ^†Group III is significantly lower than Group I, and subgroups I_A, I_B, and I_C (^††† P < 0.001). The OD (450 nm) values are shown as means ± SE