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Fig. 1 | BMC Veterinary Research

Fig. 1

From: Atypical bromethalin intoxication in a dog: pathologic features and identification of an isomeric breakdown product

Fig. 1

Brain, cortical lesions. a Gross image of brain at necropsy showing marked meningeal congestion and hemorrhages. b In the cortical grey matter are shrunken and hypereosinophilic neurons as well as mild vacuoles of the neuropil (spongiosis), H&E stain 400x. c and e) Control canine brain IHC for GFAP (red) and NeuN (black). Note intense black stain of normal neurons and scattered red staining of normal, resting astrocytes (100x and 400x). d and f): IHC for GFAP and NeuN on brain sections from the bromethalin intoxicated dog: Note marked decrease in NeuN (black) staining in neurons compared to control and increase in GFAP (red) indicating enlargement of astrocyte cell bodies and astrocytic processes in the glia limitans. (100x and 400x)

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BMC Veterinary Research

ISSN: 1746-6148

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