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Fig. 7 | BMC Veterinary Research

Fig. 7

From: Activity of the DNA minor groove cross-linking agent SG2000 (SJG-136) against canine tumours

Fig. 7

SG2000-induced γ-H2AX foci in tumour cells and peripheral blood mononuclear cells (lymphocytes) harvested from three mice carrying subcutaneous a) LMeC or b) CMeC-1 canine melanoma xenograft tumours, at 2 and 24 h following either 0.15 or 0.3 mg/kg SG2000. γH2AX foci/cell were counted in the first 50 cells and results were grouped in ranges (0, 1–5, 6–10, 11–15, 16–20, and >20 γ-H2AX foci/cell)

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