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Table 2 Enhanced immune gene induction by S. aureus in SM10 through pathogen disruption

From: Extracellular milieu grossly alters pathogen-specific immune response of mammary epithelial cells

Gene

N305

RF122

CXCL8

5.6

6.5

TNF

14. 9

5.9

IL1B

25.5

6.7

IL1A

4.2

4.0

IL6

9.4

5.4

SAA3

8.3

5.5

NOS2A

159.4

67.3

  1. Values are the ratio of increased mRNA concentration (fold over control) after 3 h stimulation with 30 μg/ml of RiboLyser lysates and the corresponding value obtained after stimulating with 30 μg/ml of the respective pathogen particles. Induction values for particles and RiboLyser extracts had been obtained in separate experiments, each strain assayed in duplicate