Cefquinome dose | AUC0–12
| Cmax
|
---|
(mg/kg of body weight) | (μg · h/mL) | (μg/mL) |
---|
0.2 | 1.346 ± 0.046 | 0.135 ± 0.004 |
0.4 | 1.553 ± 0.066 | 0.170 ± 0.007 |
0.6 | 2.802 ± 0.044 | 0.286 ± 0.001 |
0.8 | 3.693 ± 0.088 | 0.396 ± 0.008 |
1 | 4.230 ± 0.013 | 0.448 ± 0.003 |
2 | 11.157 ± 0.048 | 1.175 ± 0.024 |
4 | 20.730 ± 0.0640 | 2.069 ± 0.070 |
- The AUC0–12 and Cmax were the mean values of multiple-dose (six times). AUC0–12, area under the concentration-time curve from 0 to 12 h after every administration, was determined by use of the trapezoidal rule; the Cmax was directly from the concentration-time curve of every administration. The values shown are means ± standard deviations