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Table 3 Summary of medians, range and statistical comparisons for the Canine Brief Pain Inventory Pain Severity Scores (CBPI PSS) at D0, D14 and D28 of the study

From: A canine-specific anti-nerve growth factor antibody alleviates pain and improves mobility and function in dogs with degenerative joint disease-associated pain

Group

D0

D14

D28

D0 minus D14

Within group change P-value

D0 minus D28

Within group change P-value

NV-01

4.75 (1.75-9.00)

2.00 (0.50-6.25)

2.63 (1.00 – 7.00)

1.50 (-0.75 – 4.50)

0.012

1.50 (-0.75 – 4.00)

0.019

Placebo

3.75 (1.25-8.50)

3.00 (1.00-8.75)

3.00 (1.00 – 8.00)

0.75 (-2.50 – 4.25)

0.164

0.75 (-2.00 – 4.25)

0.347

Between group comparison P-value

0.898

0.719

0.744

0.226

 

0.210

 
  1. Decreases in scores signify improvement, and positive values for change indicate improvement. Significant P-values are denoted in bold type.