Figure 3From: DNA-based diagnosis of rare diseases in veterinary medicine: a 4.4 kb deletion of ITGB4 is associated with epidermolysis bullosa in Charolais cattle Transmission electron microscopy of the skin. Macroscopically unaffected skin from the left hind leg with a severe subepidermal cleft formation (asterisk) located in the lamina lucida of the basement membrane. The lamina densa (arrow) is attached to the dermis. E = epidermis; D = dermis. Bar = 250 nm.Back to article page