Identification of immunodominant antigens in canine leptospirosis by Multi-Antigen Print ImmunoAssay (MAPIA)

BMC Veterinary Research

Table 1 Diagnostic performance of each antigen for all the control groups studied

Antigens	P1 vs N2		P1 vs N3		P1 vs N4		P1 vs N2, N3 and N4 combined
Antigens	AUC	Se/Spe	AUC	Se/Spe	AUC	Se/Spe	AUC	Se/Spe
LigB [582-947aa] L. interrogans Pomona	0.841	63/90	0.636	27/90	0.781	43/89	0.749	40/90
LigB [131-649aa] L. interrogans Canicola	0.879	73/87	0.763	53/93	0.840	70/89	0.826	67/91
LigB [582-947aa] L. interrogans Copenhageni	0.875	67/90	0.682	27/90	0.704	33/95	0.764	37/91
LigB [131-649aa] L. interrogans Copenhageni	0.827	63/87	0.707	47/87	0.811	57/89	0.777	50/87
LigA [625-1224aa] L. interrogans Copenhageni	0.875	63/93	0.654	20/90	0.714	40/95	0.764	37/89
LipL32 L. interrogans Copenhageni	0.951	77/93	0.787	43/93	0.869	70/95	0.869	60/91
LigB [582-947aa] L. kirschneri Gryppotyphosa	0.759	63/90	0.601	27/97	0.742	53/89	0.695	40/92
LigB [131-649aa] L. kirschneri Gryppotyphosa	0.919	80/93	0.787	57/93	0.861	70/89	0.855	63/90

Se: sensitivity; Spe: specificity. Sample groups: P1, seropositive dogs; N2, housed vaccinated dogs; N3, stray dogs; N4, dogs with other febrile syndromes.

ISSN: 1746-6148