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Table 2 P values based on the ANCOVA

From: Effects of isoflurane, ketamine-xylazine and a combination of medetomidine, midazolam and fentanyl on physiological variables continuously measured by telemetry in Wistar rats

Parameter

Treatment

Induction time

Non-surgical tolerance

Surgical tolerance

Wake-up period

Recovery

Mean difference

P value

Mean difference

P value

Mean difference

P value

Mean difference

P value

Mean difference

P value

SAP (mmHg)

ISO vs. KX

-13.18

< 0.01*

-9.15

0.15

-0.58

0.88

26.46

< 0.01*

6.33

0.07

ISO vs. MMF

-33.07

< 0.01*

-45.79

< 0.01*

-63.08

< 0.01*

15.41

< 0.01*

3.54

0.03*

KX vs. MMF

-19.88

< 0.01*

-36.64

< 0.01*

-62.50

< 0.01*

-11.05

0.03*

-2.80

0.38

DAP (mmHg)

ISO vs. KX

-13.57

< 0.01*

-7.27

0.27

-1.72

0.70

16.39

< 0.01*

5.96

0.01*

ISO vs. MMF

-27.08

< 0.01*

-33.41

< 0.01*

-38.62

< 0.01*

4.83

0.21

-0.95

0.52

KX vs. MMF

-13.50

< 0.01*

-26.14

< 0.01*

-36.90

< 0.01*

-11.56

< 0.01*

-6.92

< 0.01*

MAP (mmHg)

ISO vs. KX

-13.12

< 0.01*

-7.33

0.25

-0.90

0.83

19.57

< 0.01*

6.14

0.02*

ISO vs. MMF

-29.09

< 0.01*

-37.48

< 0.01*

-46.74

< 0.01*

8.32

0.05*

0.54

0.71

KX vs. MMF

-15.98

< 0.01*

-30.16

< 0.01*

-45.84

< 0.01*

-11.25

< 0.01*

-5.60

0.03*

PP (mmHg)

ISO vs. KX

-0.76

0.59

2.10

0.26

2.68

0.15

8.41

< 0.01*

-0.44

0.80

ISO vs. MMF

-6.41

< 0.01*

-13.95

< 0.01*

-25.42

< 0.01*

11.09

< 0.01*

4.55

< 0.01*

KX vs. MMF

-5.65

< 0.01*

-16.05

< 0.01*

-28.10

< 0.01*

2.69

0.20

4.99

0.02*

HR (bpm)

ISO vs. KX

14.62

0.36

93.14

< 0.01*

144.75

< 0.01*

148.62

< 0.01*

-20.86

< 0.01*

ISO vs. MMF

85.80

< 0.01*

139.93

< 0.01*

195.12

< 0.01*

190.22

< 0.01*

13.41

0.09

KX vs. MMF

71.17

< 0.01*

46.79

< 0.01*

50.37

< 0.01*

41.60

< 0.01*

34.27

< 0.01*

BT (°C)

ISO vs. KX

0.11

0.11

0.10

0.26

-0.22

0.34

-0.56

0.08

-0.21

0.18

ISO vs. MMF

0.09

0.26

0.16

0.20

-0.19

0.52

-0.04

0.92

0.19

0.17

KX vs. MMF

-0.01

0.87

0.06

0.67

0.03

0.90

0.52

0.14

0.39

0.04*

  1. *statistically significant difference (p value ≤0.05 in bold print) based on the ANCOVA with baseline as covariate for the comparison of anaesthetic treatments.
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BMC Veterinary Research

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