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Table 2 Expression of IHC markers by diagnosed histological type of testicular tumor

From: Canine testicular tumors: two types of seminomas can be differentiated by immunohistochemistry

Histological type of tumor

Necropsy group

Biopsy group

c-KIT positive tumors/%

% of c-KIT positive cells

PLAP positive tumors/%

% of PLAP positive cells

Cytokeratin positive tumors/%

% of Cytokeratin positive cells

CD 30 positive tumors/%

% of CD 30 positive cells

c-KIT positive tumors/%

% of c-KIT positive cells

PLAP positive tumors/%

% of PLAP positive cells

Cytokeratin positive tumors/%

% of Cytokeratin positive cells

CD 30 positive tumors/%

% of CD 30 positive cells

SIMPLE TUMORS (∑)

11

39

23

<5

27

19

7

8

22

40

27

<6

33

43

8

23

MIXED TUMORS (∑)

33

23

25

<5

66

25

8

5

44

26

22

<7

44

46

11

30

LCT simple

5

5

21

<5

15

16

5

10

0

0

16

<5

20

60

6

30

with SCT

20

20

40

<5

60

23

20

5

0

0

0

0

100

50

0

0

with IT SEM

33

10

0

0

60

17

0

0

100

20

100

10

100

5

0

0

with DIF SEM

50

60

0

0

40

40

0

0

75

28

0

0

0

0

0

 

SCT simple

0

0

28

<5

71

32

14

10

6

5

31

<5

62

51

12

27

with LCT

20

20

40

<5

60

23

20

5

0

0

0

0

100

50

0

0

with DIF SEM

50

5

50

5

100

30

0

0

0

0

25

5

50

65

25

30

IT SEM simple

14

5

14

5

28

5

0

0

0

0

33

10

33

5

0

0

with LCT

33

10

0

0

60

17

0

0

100

20

100

10

100

5

0

0

DIF SEM simple

50

90

25

5

25

5

25

5

45

43

15

11

10

12

0

0

with SCT

50

5

50

5

100

30

0

0

0

0

25

5

50

65

25

30

with LCT

50

60

0

0

40

40

0

0

75

28

0

0

0

0

0

 

PNST

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

TERAT

0

0

0

0

0

0

0

0

0

20

0

<5

100

50

100

10

IGCNU

16

 

33

<5

16

5

0

0

0

0

100

5

0

0

0

0

MET. T. LYMPH

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

Total

16

32

23

<5

35

21

7

7

26

36

26

<6

29

44

8

25

  1. Note: ∑, sum; DIF SEM, diffuse seminoma; IGCNU, intratubular germ cell neoplasia of undifferentiated origin; IT SEM, intratubular seminoma; LCT, Leydig cell tumors; MET. T. LYMPH, metastatic tumor – lymphoma; PLAP, placental alkaline phosphatase; PNST, peripheral nerve sheat tumor; SCT, Sertoli cell tumor; TERAT, teratoma.