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Table 1 Serum biochemical and hematological parameters from healthy reference cows and cows with fatty liver

From: Serum paraoxonase-1 as biomarker for improved diagnosis of fatty liver in dairy cows

 

Control ( n=46)

Fatty liver ( n=46)

% change

Distribution

P value ≤

Biochemical parameters

    

Paraoxonase (U/mL)

82.11 ± 22.42

38.47 ± 13.40

−53.14

0.029

0.001

Lactonase (U/mL)

5.82 ± 1.70

2.56 ± 1.11

−55.86

0.043

0.001

Arylesterase (U/mL)

47.92 ± 7.36

30.44 ± 7.88

−36.48

0.028

0.001

AST (U/L)

67.84 ± 14.53

136.78 ± 68.14

101.62

0.000

0.001

GGT (U/L)

44.18 ± 10.43

49.93 ± 30.25

13.02

0.068

0.903

ALP (U/L)

232.45 ± 73.10

225.69 ± 84.07

−2.907

0.048

0.871

LCAT (470/390)

3.80 ± 1.10

3.20 ± 0.84

−15.81

0.000

0.015

T. Bil (μmol/L)

5.30 ± 2.22

18.31 ± 7.69

245.28

0.000

0.001

NEFA (mmol/L)

0.22 ± 0.20

1.19 ± 0.60

440.90

0.000

0.001

BHBA (mmol/L)

0.725 ± 0.31

2.94 ± 1.77

305.51

0.000

0.001

T.CHOL (mmol/L)

4.71 ± 1.17

1.58 ± 0.61

−66.45

0.171

0.001

HDL (mmol/L)

1.94 ± 0.71

1.19 ± 0.001

−38.65

0.048

0.001

VLDL (mmol/L)

0.141 ± 0.05

0.08 ± 0.05

−43.26

0.808

0.001

LDL (mmol/L)

2.72 ± 1.71

0.44 ± 0.37

−83.82

0.001

0.001

TG (mmol/L)

0.30 ± 0.12

0.39 ± 0.14

30.00

0.808

0.002

FC (mmol/L)

0.94 ± 0.35

0.37 ± 0.15

−60.63

0.135

0.001

CE (mmol/L)

3.84 ± 1.49

1.20 ± 0.53

−68.75

0.177

0.001

E. ratio

80.12 ± 3.73

75.12 ± 9.95

−6.24

0.000

0.014

PL (mmol/L)

2.89 ± 1.05

0.85 ± 0.29

−70.58

0.036

0.001

TP (g/L)

70.92 ± 5.60

69.10 ± 6.8

−2.56

0.005

0.749

ALB (g/L)

35.5 6 ± 2.56

32.59 ± 3.31

−8.565

0.018

0.001

AG ratio

1.032 ± 0.19

0.91 ± 0.18

−11.614

0.570

0.004

GLU (mmol/L)

2.55 ± 0.61

2.74 ± 0.15

7.45

0.004

0.739

BUN (mmol/L)

12.69 ± 8.49

5.40 ± 6.70

−57.44

0.000

0.083

Ca (mmol/L)

2.56 ± 0.15

2.21 ± 0.27

−13.67

0.000

0.001

P (mmol/L)

1.92 ± 0.31

2.05 ± 0.90

6.77

0.462

0.657

Mg (mmol/L)

1.05 ± 0.12

0.90 ± 0.12

−14.28

0.000

0.001

Hematological parameters

     

WBCs (109/L)

8.045 ± 1.88

8.87 ± 5.48

10.267

0.000

0.188

RBCs (1012/L)

5.94 ± 0.67

5.35 ± 1.18

−9.951

0.937

0.002

Hgb (g/L)

98.52 ± 10.13

98.17 ± 21.60

−0.441

0.637

0.795

HCT%

26.86 ± 4.26

26.90 ± 2.16

0.138

0.015

0.924

MCV (fL)

45.65 ± 4.95

50.21 ± 6.14

9.990

0.239

0.001

MCH (pg)

16.65 ± 1.70

18.33 ± 1.57

10.132

0.948

0.001

MCHC (g/L)

36.66 ± 2.84

35.96 ± 5.66

−1.909

0.284

0.478

PLT (109/L)

398.28 ± 114.99

351.36 ± 99.68

−11.779

0.484

0.001

  1. Data are presented as mean values ± standard deviation of mean.
  2. AST, aspartate aminotransferase; GGT, gamma glutamyltransferase; ALP, alkaline phosphatase; LCAT, lecithin-cholesterol acyltransferase; T. Bil, total bilirubin; NEFA, non-esterified fatty acids; BHBA, beta-hydroxybutyrate; T.CHOL, total cholesterol; HDL, high-density lipoprotein; VLDL, very low-density lipoprotein; LDL, low-density lipoprotein; TG, triglyceride; FC, free cholesterol; CE, cholesteryl ester; E. ratio, ester ratio; PL, phospholipids; TP, total protein; ALB, albumin; AG, albumin/globulin ratio; GLU, Glucose; BUN, blood urea nitrogen; Ca, total serum calcium; P, inorganic phosphorus; Mg, magnesium; WBC, total white blood cell count; RBC, total red blood cell count; Hg, hemoglobin content; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; and PLT, platelet count.