Urodynamic investigation by telemetry in Beagle dogs: validation and effects of oral administration of current urological drugs: a pilot study

Table 5 Urethral EMG: evolution of the EMGi/minute values during the different drug administrations

Drugs	EMGi/minute: Pre-micturition (mV sec)				EMGi/minute: Post-micturition (mV sec)
	Day 0	Day 1	Day 8	Day 15	Day 0	Day 1	Day 8	Day 15
Phenylpropanolamine	0.55 ± 0.1	0.54 ± 0.1	0.82 ± 0.11	0.99 ± 0.12	0.60 ± 0.01	0.59 ± 0.1	0.62 ± 0.11	0.51 ± 0.12
Oestriol	0.49 ± 0.11	0.58 ± 0.1	0.81 ± 0.12	0.51 ± 0.11	0.51 ± 0.11	0.6 ± 0.11	0.64 ± 0.12	0.49 ± 0.11
Oxybutynin	0.57 ± 0.12	0.53 ± 0.10	0.46 ± 0.12	0.52 ± 0.11	0.50 ± 0.12	0.64 ± 0.10	0.55 ± 0.12	0.48 ± 0.11
Bethanechol	0.41 ± 0.12	0.62 ± 0.09	0.55 ± 0.11	0.57 ± 0.10	0.50 ± 0.12	0.67 ± 0.09	0.49 ± 0.11	0.49 ± 0.10
Duloxetine	0.45 ± 0.11	0.51 ± 0.11	0.54 ± 0.10	0.60 ± 0.11	0.47 ± 0.11	0.56 ± 0.11	0.49 ± 0.10	0.56 ± 0.11

EMGi/minute = integrated EMG during the minute preceding or following the micturition episode.
Data are expressed as LSMean ± SEM.

ISSN: 1746-6148