Table 3 Owner-reported pruritus VAS scores and reduction from baseline following treatment
Day | Treatment (n = 22) | Score | Score change from baseline (%) | p-value | ||||
|---|---|---|---|---|---|---|---|---|
Mean2 | Median | s.d. | Min | Max | Mean (95% CI) | |||
0 | Cyclosporine A | 79.28 | 80.58 | 12.45 | 52.60 | 98.92 | - | - |
Cyclosporine A and prednisolone | 73.90 | 73.12 | 11.83 | 50.75 | 100.00 | - | ||
3-4 | Cyclosporine A | 77.43 | 79.03 | 11.42 | 48.50 | 95.02 | −1.18 (−7.8,5.5) | 0.0008 |
Cyclosporine A and prednisolone | 47.65 | 50.00 | 22.86 | 10.95 | 96.79 | −36.33 (−48.7,-24.0) | ||
7-8 | Cyclosporine A | 67.79 | 69.65 | 14.62 | 38.71 | 95.02 | −13.04 (−22.3,-3.8) | 0.0008 |
Cyclosporine A and prednisolone | 29.21 | 29.50 | 20.46 | 1.99 | 72.04 | −60.61 (−73.3,-47.9) | ||
10-11 | Cyclosporine A | 65.81 | 67.99 | 13.47 | 36.56 | 87.06 | −15.31 (−24.2,-6.5) | 0.0008 |
Cyclosporine A and prednisolone1 | 23.08 | 16.13 | 22.97 | 0.00 | 74.63 | −68.73 (−82.7,-54.7) | ||
14 ± 1 | Cyclosporine A | 58.69 | 57.53 | 18.03 | 26.87 | 93.03 | −24.57 (−34.9,-14.2) | 0.0008 |
Cyclosporine A and prednisolone | 20.37 | 12.90 | 20.22 | 0.00 | 75.62 | −72.79 (−84.4,-61.1) | ||
17-18 | Cyclosporine A | 50.45 | 47.54 | 19.71 | 20.40 | 88.56 | −34.62 (−47.0,-22.3) | 0.0008 |
Cyclosporine A and prednisolone | 19.33 | 10.75 | 19.50 | 0.00 | 70.00 | −73.57 (−84.9,-62.3) | ||
21-22 | Cyclosporine A | 48.33 | 47.79 | 20.26 | 16.13 | 88.56 | −37.00 (−50.1,-23.9) | 0.0128 |
Cyclosporine A and prednisolone | 21.23 | 11.29 | 24.84 | 0.00 | 84.58 | −70.55 (−85.5,-55.6) | ||
24-25 | Cyclosporine A | 43.69 | 42.36 | 24.29 | 3.23 | 88.56 | −42.41 (−58.2,-26.6) | 0.0240 |
Cyclosporine A and prednisolone | 19.90 | 10.75 | 24.42 | 0.00 | 93.03 | −73.10 (−86.9,-59.3) | ||
28 ± 2 | Cyclosporine A1 | 43.44 | 43.01 | 25.09 | 3.23 | 89.05 | −42.36 (−58.2,-26.5) | 0.2160 |
Cyclosporine A and prednisolone | 26.26 | 15.05 | 28.54 | 0.00 | 94.03 | −65.12 (−81.1,-9.1) | ||