Detection and comparison of microRNA expression in the serum of Doberman Pinschers with dilated cardiomyopathy and healthy controls

Table 3 Time course of electrocardiographic and echocardiographic changes of dogs with DCM starting from time of diagnosis

Sample name	Number of visits	VPCs/24 hours	Maximal velocity of VPCs (bpm)	LVEDV (ml/m²)	LVESV (ml/m²)	EF (%)
DoCM 5	1^st visit	254	240	119.20	65.80	44.67
	2^nd visit	107	203	94.60	56.70	40.08
	3^rd visit*	161	200	116.80	73.10	37.41
	4^th visit	199	214	110.90	62.40	43.72
DoCM 6	1^st visit	13641	300	105.70	63.40	39.97
	2^nd visit	10355	319	124.20	79.40	36.06
	3^rd visit*	10005	300	122.50	68.40	44.21
	4^th visit	14	196	112.30	77.60	30.93
	5^th visit	22	230	132.50	78.20	41.01
	6^th visit	24	300	142.50	94.50	33.73
DoCM 7	1^st visit	1940	230	112.70	72.90	35.31
	2^nd visit	2478	275	121.70	82.40	32.31
	3^rd visit	17	273	116.40	79.90	31.40
	4^th visit*	616	180	117.30	75.00	36.04
	5^th visit	3010	250	151.20	108.50	28.24
	6^th visit	135	300	143.70	123.30	14.19
DoCM 8	1^st visit	302	300	116.00	72.30	37.68
	2^nd visit	9	265	109.90	59.80	45.62
	3^rd visit*	209	202	124.60	73.50	41.01
	4^th visit	7295	300	99.00	50.50	48.93

DCM: Dilated cardiomyopathy, DoCM: Dilated Cardiomyopathy in Doberman Pinschers, VPCs: Ventricular premature complexes, VPCs/24 hours: ventricular premature complexes in 24 hours; bpm: beats per minute; LVEDV: left ventricular end-diastolic volume; LVESV: left ventricular end-systolic volume; EF: left ventricular ejection fraction, *: visit of serum sampling for microRNA analysis.

ISSN: 1746-6148