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Table 1 Inoculum groups and median survival times after serial intracerebral passage in Tg338 mice

From: Transmissibility of caprine scrapie in ovine transgenic mice

Inoculum groups

Passage

Recipients tested1

Median survival time

95%

LCL-UCL2

Donor

species

Donor

case number

 

(n, c)

(dpi)

(dpi)

goat

30–75

P1

10, 0

166.0

166.0–180.0

3538

10, 0

253.0

199.0–331.0

3558

9, 0

253.0

199.0–280.0

sheep

3178

7, 3

241.0

180.0–257.0

goat

30–75

P2

11, 3

130.0

125.0–130.0

3538

22, 2

137.0

133.0–137.0

3558

9, 0

137.0

133.0–139.0

sheep

3178

 

19, 0

135.0

129.0–136.0

  1. 1 Kaplan-Meier product-limit estimation of survival functions for n non-censored and c censored recipients per isolate.
  2. 295% lower and upper confidence limits (UCL, LCL) were determined using the log(−log) transform.