No | Fold change | Gene ID | Gene name | Molecular function | Biological process |
---|---|---|---|---|---|
1 | 2.17 | EPS8L1 | Epidermal growth factor receptor kinase substrate 8-like protein 1 | intracellular signaling cascade; cell motion; signal transduction | |
2 | 2.17 | OR4X1 | Olfactory receptor 4X1 | ||
3 | 2.18 | C2orf61 | Uncharacterized protein C2orf61 | ||
4 | 2.18 | DSN1 | Kinetochore-associated protein DSN1 homolog | ||
5 | 2.18 | PFAS | Phosphoribosylformylglycinamidine synthase | ligase activity | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
6 | 2.18 | SLC5A2 | Sodium/glucose cotransporter 2 | carbohydrate transmembrane transporter activity; cation transmembrane transporter activity | cation transport; extracellular transport; amino acid transport; carbohydrate metabolic process; cellular amino acid and derivative metabolic process |
7 | 2.18 | TMEM138 | Transmembrane protein 138 | ||
8 | 2.19 | FOLR1 | Folate receptor alpha | receptor activity;transmembrane transporter activity | vitamin transport |
9 | 2.19 | MFN2 | Mitofusin-2 | hydrolase activity, acting on ester bonds; phosphatase activity | intracellular protein transport; organelle organization; mitochondrion organization |
10 | 2.19 | NDRG3 | Protein NDRG3 | ||
11 | 2.19 | UNC13D | Protein unc-13 homolog D | intracellular protein transport; exocytosis | |
12 | 2.20 | GOLPH3 | Golgi phosphoprotein 3 | ||
13 | 2.20 | SLC22A13 | Solute carrier family 22 member 13 | ATPase activity, coupled to transmembrane movement of substances; ligase activity; carbohydrate transmembrane transporter activity; cation transmembrane transporter activity | cation transport; anion transport; extracellular transport; carbohydrate transport; carbohydrate metabolic process |
14 | 2.20 | USP54 | Inactive ubiquitin carboxyl-terminal hydrolase 54 | ubiquitin-protein ligase activity | protein metabolic process |
15 | 2.22 | NMI | N-myc-interactor | DNA binding; transcription factor activity; transcription cofactor activity | response to interferon-gamma; intracellular signaling cascade; signal transduction; cellular defense response |
16 | 2.22 | PDCD1 | Programmed cell death protein 1 | ||
17 | 2.22 | SNRPN | Small nuclear ribonucleoprotein-associated protein N | RNA splicing factor activity, transesterification mechanism; RNA binding | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
18 | 2.23 | SPSB1 | SPRY domain-containing SOCS box protein 1 | ||
19 | 2.24 | ADAMTS15 | A disintegrin and metalloproteinase with thrombospondin motifs 15 | peptidase activity; protein binding; peptidase inhibitor activity | fertilization; signal transduction; cell-matrix adhesion; cell-cell adhesion; protein metabolic process; signal transduction; ectoderm development; mesoderm development; skeletal system development; angiogenesis; nervous system development; muscle organ development |
20 | 2.24 | MTRF1L | Peptide chain release factor 1-like, mitochondrial | translation factor activity, nucleic acid binding; translation release factor activity | protein metabolic process |
21 | 2.24 | TOMM7 | Mitochondrial import receptor subunit TOM7 homolog | transmembrane transporter activity | intracellular protein transport |
22 | 2.25 | ATG7 | Autophagy-related protein 7 | ligase activity | intracellular signaling cascade; coenzyme metabolic process; protein metabolic process; signal transduction |
23 | 2.25 | C19orf52 | Uncharacterized protein C19orf52 | ||
24 | 2.25 | USF2 | Upstream stimulatory factor 2 | DNA binding; transcription factor activity | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; lipid metabolic process |
25 | 2.26 | POGK | Pogo transposable element with KRAB domain | DNA binding | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; ectoderm development; nervous system development |
26 | 2.26 | ZNF804B | Zinc finger protein 804B | ||
27 | 2.27 | CD274 | Programmed cell death 1 ligand 1 | ubiquitin-protein ligase activity; receptor activity; DNA binding; receptor binding; transcription factor activity; transcription cofactor activity | immune system process; neurotransmitter secretion; intracellular protein transport; exocytosis; signal transduction; synaptic transmission; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; protein metabolic process; cell-cell signaling; organelle organization; establishment or maintenance of chromatin architecture; mesoderm development; mammary gland development; response to stress; cellular defense response |
28 | 2.27 | FAM132B | Protein FAM132B | ||
29 | 2.27 | STK32C | Serine/threonine-protein kinase 32 C | kinase activity | cell cycle; intracellular signaling cascade; protein metabolic process; cell cycle; signal transduction |
30 | 2.28 | CADM4 | Cell adhesion molecule 4 | receptor activity | |
31 | 2.28 | GLIPR2 | Golgi-associated plant pathogenesis-related protein 1 | immune system process | |
32 | 2.28 | GPR160 | Probable G-protein coupled receptor 160 | ||
33 | 2.29 | GALNT2 | Polypeptide N-acetylgalactosaminyltransferase 2 soluble form | transferase activity, transferring glycosyl groups | carbohydrate metabolic process; protein metabolic process |
34 | 2.29 | KRT20 | Keratin, type I cytoskeletal 20 | structural constituent of cytoskeleton | cellular component morphogenesis; cellular component morphogenesis; ectoderm development; cellular component morphogenesis |
35 | 2.29 | PTPN6 | Tyrosine-protein phosphatase non-receptor type 6 | hydrolase activity, acting on ester bonds; phosphatase activity; receptor activity | immune system process; intracellular protein transport; mitosis; cell surface receptor linked signal transduction; intracellular signaling cascade; cell-matrix adhesion; cell-cell adhesion; protein metabolic process; cytokinesis; cell motion; mitosis; signal transduction; nervous system development; cellular glucose homeostasis |
36 | 2.29 | SOHLH1 | Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 | ||
37 | 2.31 | CENPM | Centromere protein M | ||
38 | 2.31 | HPCAL1 | Hippocalcin-like protein 1 | calcium ion binding; calmodulin binding; small GTPase regulator activity | visual perception; sensory perception; cell surface receptor linked signal transduction; signal transduction |
39 | 2.31 | TMEM81 | Transmembrane protein 81 | ||
40 | 2.32 | HOXA1 | Homeobox protein Hox-A1 | DNA binding; transcription factor activity | female gamete generation; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; segment specification; ectoderm development; gut mesoderm development; embryonic development; skeletal system development; angiogenesis; nervous system development; muscle organ development |
41 | 2.32 | SMO | Smoothened homolog | G-protein coupled receptor activity; receptor binding | cell surface receptor linked signal transduction; cell-cell signaling |
42 | 2.33 | LAMP2 | Lysosome-associated membrane glycoprotein 2 | lysosomal transport; intracellular protein transport; protein metabolic process | |
43 | 2.33 | RNF121 | RING finger protein 121 | ubiquitin-protein ligase activity | protein metabolic process |
44 | 2.34 | PLA2G2E | Group IIE secretory phospholipase A2 | hydrolase activity, acting on ester bonds | signal transduction; lipid metabolic process; signal transduction |
45 | 2.34 | POU6F2 | POU domain, class 6, transcription factor 2 | DNA binding; transcription factor activity | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
46 | 2.34 | PPP2R4 | Serine/threonine-protein phosphatase 2A regulatory subunit B' | protein binding;phosphatase activator activity; phosphatase regulator activity | protein metabolic process |
47 | 2.34 | STX5 | Syntaxin-5 | SNAP receptor activity | neurotransmitter secretion; intracellular protein transport; exocytosis; endocytosis; synaptic transmission; cell-cell signaling |
48 | 2.35 | DMC1 | Meiotic recombination protein DMC1/LIM15 homolog | hydrolase activity; DNA binding | immune system process; meiosis; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; meiosis; response to stress |
49 | 2.35 | ERRFI1 | ERBB receptor feedback inhibitor 1 | signal transduction;signal transduction | |
50 | 2.36 | TSPYL4 | Testis-specific Y-encoded-like protein 4 | protein binding; phosphatase inhibitor activity; phosphatase regulator activity | apoptosis; cell cycle; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; protein metabolic process; cell cycle; organelle organization; establishment or maintenance of chromatin architecture |
51 | 2.37 | USF1 | Upstream stimulatory factor 1 | DNA binding; transcription factor activity | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; lipid metabolic process |
52 | 2.40 | ARFGAP3 | ADP-ribosylation factor GTPase-activating protein 3 | nucleic acid binding; protein binding; small GTPase regulator activity | cell surface receptor linked signal transduction; cell adhesion |
53 | 2.40 | CNBP | Cellular nucleic acid-binding protein | nucleic acid binding | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; lipid metabolic process |
54 | 2.40 | NKD1 | Protein naked cuticle homolog 1 | ||
55 | 2.41 | MRPL51 | 39S ribosomal protein L51, mitochondrial; | structural constituent of ribosome; nucleic acid binding | protein metabolic process |
56 | 2.41 | OPRK1 | Kappa-type opioid receptor | G-protein coupled receptor activity | sensory perception; cell surface receptor linked signal transduction; synaptic transmission; cell motion; signal transduction; cell-cell signaling |
57 | 2.41 | PTX3 | Pentraxin-related protein PTX3 | immune response; response to stress; defense response to bacterium | |
58 | 2.42 | GPRC5B | G-protein coupled receptor family C group 5 member B | G-protein coupled receptor activity | cell surface receptor linked signal transduction; signal transduction |
59 | 2.42 | NGLY1 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase | hydrolase activity | protein metabolic process |
60 | 2.43 | CAPN12 | Calpain-12 | peptidase activity; calcium ion binding; calmodulin binding; calcium-dependent phospholipid binding | induction of apoptosis; intracellular signaling cascade; protein metabolic process; signal transduction |
61 | 2.43 | POLD1 | DNA polymerase delta catalytic subunit | DNA-directed DNA polymerase activity; hydrolase activity, acting on ester bonds; nucleic acid binding | cell cycle; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; cell cycle |
62 | 2.44 | TBC1D8 | TBC1 domain family member 8 | hydrolase activity; protein binding; small GTPase regulator activity | intracellular protein transport; exocytosis; cellular component morphogenesis |
63 | 2.45 | DHRS11 | Dehydrogenase/reductase SDR family member 11 | oxidoreductase activity | visual perception; sensory perception; lipid metabolic process |
64 | 2.46 | LZTR1 | Leucine-zipper-like transcriptional regulator 1 | structural constituent of cytoskeleton; DNA binding; chromatin binding; protein binding; small GTPase regulator activity; transcription factor activity | spermatogenesis; immune system process; intracellular protein transport; vesicle-mediated transport; cell cycle; nitrogen compound metabolic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; protein metabolic process |
65 | 2.46 | OR6V1 | Olfactory receptor 6 V1 | ||
66 | 2.47 | C12orf65 | Uncharacterized protein C12orf65 | translation factor activity, nucleic acid binding; translation release factor activity | protein metabolic process |
67 | 2.47 | C2orf56 | Protein midA homolog, mitochondrial | ||
68 | 2.47 | RBM42 | RNA-binding protein 42 | RNA splicing factor activity, transesterification mechanism; DNA binding; RNA binding | spermatogenesis; neurological system process; cell cycle; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; protein metabolic process; ectoderm development; nervous system development |
69 | 2.48 | DPM2 | Dolichol phosphate-mannose biosynthesis regulatory protein | ||
70 | 2.48 | TDRD12 | Tudor domain-containing protein 12 | RNA helicase activity; translation factor activity, nucleic acid binding; translation initiation factor activity | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; protein metabolic process |
71 | 2.53 | CCDC85B | Coiled-coil domain-containing protein 85B | ||
72 | 2.54 | MATN1 | Cartilage matrix protein | extracellular matrix structural constituent | immune system process; sensory perception of sound;sensory perception; signal transduction; cell-cell adhesion; cellular component morphogenesis; mesoderm development; skeletal system development; blood coagulation |
73 | 2.55 | FLYWCH1 | FLYWCH-type zinc finger-containing protein 1 | ||
74 | 2.55 | PLA2G2D | Group IID secretory phospholipase A2 | hydrolase activity, acting on ester bonds | signal transduction; lipid metabolic process; signal transduction |
75 | 2.56 | TMEM38A | Trimeric intracellular cation channel type A | ||
76 | 2.58 | RGS11 | Regulator of G-protein signaling 11 | protein binding;small GTPase regulator activity | cell surface receptor linked signal transduction; signal transduction; dorsal/ventral axis specification |
77 | 2.61 | BAHD1 | Bromo adjacent homology domain-containing 1 protein | DNA binding | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
78 | 2.67 | CHD5 | Chromodomain-helicase-DNA-binding protein 5 | DNA helicase activity; nucleic acid binding | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; organelle organization; establishment or maintenance of chromatin architecture |
79 | 2.67 | CHD5 | Tryptophan-rich protein; | structural constituent of ribosome; nucleic acid binding | protein metabolic process |
80 | 2.67 | CYP39A1 | Cytochrome P450 39A1 | oxidoreductase activity | respiratory electron transport chain; lipid metabolic process |
81 | 2.68 | SUDS3 | Sin3 histone deacetylase corepressor complex component SDS3 | cell cycle | |
82 | 2.69 | C16orf62 | UPF0505 protein C16orf62 | ||
83 | 2.69 | FLOT2 | Flotillin-2 | intracellular protein transport; vesicle-mediated transport | |
84 | 2.69 | NINJ1 | Ninjurin-1 | neurological system process; cell adhesion; cell adhesion; ectoderm development; nervous system development | |
85 | 2.70 | FAM84A | Protein FAM84A | ||
86 | 2.71 | PAF1 | RNA polymerase II-associated factor 1 homolog | ||
87 | 2.71 | PAF1 | Peroxisome assembly factor 1 | protein metabolic process | |
88 | 2.77 | POLR2F | DNA-directed RNA polymerases I, II, and III subunit | DNA-directed RNA polymerase activity; nucleic acid binding | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
89 | 2.78 | C12orf34 | Uncharacterized protein C12orf34 | ||
90 | 2.80 | GGT6 | Gamma-glutamyltransferase 6 light chain | acyltransferase activity; peptidase activity | cellular amino acid and derivative metabolic process; protein metabolic process |
91 | 2.83 | TSC22D4 | TSC22 domain family protein 4 | DNA binding; transcription factor activity | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
92 | 2.84 | CLRN2 | Clarin-2 | ||
93 | 2.92 | KCNS1 | Potassium voltage-gated channel subfamily S member 1 | cation transmembrane transporter activity; voltage-gated potassium channel activity; cation channel activity | muscle contraction; blood circulation; neuronal action potential propagation; cation transport; signal transduction; synaptic transmission; signal transduction; cell-cell signaling |
94 | 2.94 | OR51T1 | Olfactory receptor 51 T1 | ||
95 | 2.96 | OR51I1 | Olfactory receptor 51I1 | ||
96 | 3.01 | ZNF135 | Zinc finger protein 135 | DNA binding;transcription factor activity | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
97 | 3.03 | QDPR | Dihydropteridine reductase | oxidoreductase activity | cellular amino acid and derivative metabolic process |
98 | 3.11 | C9 | Complement component C9b | peptidase activity; receptor activity | complement activation; signal transduction; cell-cell adhesion; protein metabolic process; signal transduction; response to stimulus |
99 | 3.16 | VDAC1 | Voltage-dependent anion-selective channel protein 1 | voltage-gated ion channel activity; anion channel activity | anion transport |
100 | 3.85 | FDX1L | Adrenodoxin-like protein, mitochondrial | oxidoreductase activity | respiratory electron transport chain; ferredoxin metabolic process; vitamin metabolic process; lipid metabolic process; protein metabolic process |