Table 4 Morphology score criteria applied in the initial media testing
score | Proliferation (P0) | Proliferation (P1) | Vacuole formation | Phenotype |
|---|---|---|---|---|
3 | Continuous margin of cells around explants | > 90% confluence | no vacuoles | - |
2 | Discontinuous margin of cells around explants | 70%-90% confluence | < 10% cells vacuolated | epitheloid phenotype |
1 | single cells and small clusters of cells around explants | < 70% confluence | > 10% cells vacuolated | - |
0 | not assessable, all or many cells dead | not assessable, all or many cells dead | not assessable, all or many cells dead | fibroblastoid phenotype |