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Table 6 Age, body mass and selected laboratory parameters in relation to the outcome of therapy

From: Construction and validation of a decision tree for treating metabolic acidosis in calves with neonatal diarrhea

Parameter

Successfully treated

Overdosed calves

p value

(BE −5 to +5 mmol/l)

(BE > +5 mmol/l)

n = 53

n = 55

On admission

 Age  (days)

10.0 (6.5/14.0)

8.0 (5.0/11.0)

0.046

 Body mass  (kg)

43.0 (38.8/48.7)

42.2 (38.2/47.6)

0.537

 Base excess  (mmol/l)

−14.5 (−19.4/-5.1)

−1.0 (−10.4/5.8)

< 0.001

 HCO3-  (mmol/l)

15.8 (9.9/22.2)

25.5 (18.9/31.3)

< 0.001

 Venous PCO2  (mm Hg)

47.3 (37.6/56.1)

56.4 (48.5/61.2)

< 0.001

 D-lactate  (mmol/l)

5.0 (1.1/10.3)

0.8 (0.4/3.1)

< 0.001

 L-lactate  (mmol/l)

1.3 (0.7/3.3)

2.7 (1.3/5.2)

0.002

 Anion gap  (mEq/l)

24.4 (20.4/27.9)

16.2 (12.0/27.5)

0.008

 Sodium  (mmol/l)

136.3 (130.8/140.3)

131.6 (129.1/135.4)

0.002

 Chloride  (mmol/l)

101.0 (95.0/107.0)

95.0 (88.0/98.0)

< 0.001

 Potassium  (mmol/l)

4.8 (4.3/6.0)

5.2 (4.5/6.8)

0.153

 Ionized  Calcium  (mmol/l)

1.3 (1.2/1.3)

1.2 (1.1/1.3)

0.004

After 24 hours

 Base excess  (mmol/l)

1.5 (−0.8/3.8)

8.0 (6.4/10.3)

< 0.001

 HCO3- (mmol/l)

27.6 (25.3/29.7)

34.4 (32.3/36.1)

< 0.001

 Venous PCO2  (mm Hg)

53.2 (48.9/57.4)

59.9 (55.5/63.7)

< 0.001

 D-lactate  (mmol/l)

2.1 (0.5/4.1)

0.4 (0.1/1.1)

< 0.001

 L-lactate  (mmol/l)

1.3 (1.0/2.2)

1.5 (1.1/2.1)

0.747

 Anion gap  (mEq/l)

12.7 (10.0/14.8)

9.0 (6.6/11.6)

< 0.001

 Sodium  (mmol/l)

135.0 (133.0/140.0)

135.9 (132.9/138.3)

0.768

 Chloride  (mmol/l)

101.0 (99.0/106.0)

97.0 (95.0/99.0)

< 0.001

 Potassium  (mmol/l)

4.5 (4.2/4.9)

4.6 (4.2/4.9)

0.507

 Ionized  Calcium  (mmol/l)

1.2 (1.1/1.3)

1.2 (1.1/1.2)

0.283

  1. Values are given as medians and 25-/75-quartiles.