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Table 3 mRNA expression of MMPs and inhibitors in control mammary glands and benign and malignant mammary tumors.

From: Matrix metalloproteinases and their inhibitors in canine mammary tumors

Gene

mRNA expression

-fold changes (arbitrary units)

 

Control mammary gland

Benign tumors

Malignant tumors

MMP-2

1.00 ± 0.46

1.01 ± 0.18

0.76 ± 0.12

MMP-9

1.00 ± 0.30

9.95 ± 4.40

7.23 ± 1.58

MMP-13

1.00 ± 0.28

2.08 ± 0.70

1.27 ± 0.25

MT1-MMP

1.00 ± 0.24

13.26 ± 6.09

2.82 ± 0.64

TIMP-1

1.00 ± 0.17

4.96 ± 1.27

3.97 ± 0.66

TIMP-2

1.00 ± 0.34

0.49 ± 0.09

0.60 ± 0.09

TIMP-3

1.00 ± 0.35

4.16 ± 1.62

2.38 ± 0.65

RECK

1.00 ± 0.52

3.41 ± 1.77

0.51 ± 0.10

  1. Data are expressed as the mean ± SEM.