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Figure 1 | BMC Veterinary Research

Figure 1

From: Comparison of strategies for substantiating freedom from scrapie in a sheep flock

Figure 1

Duration of the qualification process for substantiating scrapie freedom. Results obtained in simulated flocks from a susceptible (left: 30% susceptibility alleles and 10% resistance alleles, 50 flocks) and from a resistant population (right: 10% susceptibility alleles and 30% resistance alleles, 50 flocks) according to the qualification strategy: (i) full genotyping (circles) with (A1: solid line, filled symbol) or without (A2: dashed line, hollow symbol) negative test results for culled animals, (ii) genotyping and negative test result for each culled animal (squares) with (B1: solid line, filled symbol) or without (B2: dashed line, hollow symbol) known flock pedigree, and (iii) genotyping of founders animals with known flock pedigree (triangles) with (C1: solid line, filled symbol) or without (C2: dashed line, hollow symbol) negative test result for culled animals). The design prevalence is 1%.

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