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Table 1 Top 100 genes identified in Duroc.

From: Gene expression profiles in liver of pigs with extreme high and low levels of androstenone

ID

Name

gene_id

FoldChange

adj.P.Val

103725

Cytochrome P450 2C49 (CYP2C49)

NM_214420.1

1.227

8.26e-24

104194

Cytochrome P450 2C49 (CYP2C49)

NM_214420.1

0.853

4.98e-20

102872

Glycine-N-acyltransferase (GLYAT)

NM_201648.1

1.113

1.27e-19

103265

Cytochrome P450 2C49 (CYP2C49)

NM_214420.1

1.480

4.76e-18

103234

Hepatic flavin-containing monooxygenase (FMO) (FMO1)

NM_214064.1

1.179

2.28e-17

206700

Cytochrome P450 2C49 (CYP2C49)

NM_214420.1

1.099

2.71e-16

102682

Serum amyloid P component (APCS)

NM_213887.1

1.294

2.71e-16

102284

Sterile alpha motif domain containing 8 (Samd8)

NM_026283.2

0.969

3.44e-16

102668

Hepatic flavin-containing monooxygenase (FMO) (FMO1)

NM_214064.1

1.271

8.01e-16

100748

Regulatory factor X domain containing 2 (RFXDC2)

NM_022841.3

0.594

7.47e-14

206864

Similar to Alcohol dehydrogenase 6 (LOC523510)

XM_601810.2

-0.925

3.49e-13

102390

Cytochrome P450 2C49 (CYP2C49)

NM_214420.1

1.152

5.05e-13

102098

Carnitine O-octanoyltransferase (CROT)

NM_021151.2

0.886

5.30e-13

102991

Cytochrome P450. family 2. subfamily E. polypeptide 1 (CYP2E1)

NM_214421.1

-1.040

2.17e-12

216026

216026

 

-0.728

3.72e-12

102413

Small nuclear RNA activating complex. polypeptide 1. 43 kDa (SNAPC1)

NM_003082.2

0.994

4.84e-12

103432

103432

 

0.527

2.07e-11

210250

Metallothionein (MT1A)

NM_001001266.1

-0.965

3.09e-11

103062

FKBP1A-like (LOC654323)

NM_001038000.1

-1.078

3.09e-11

103279

Orosomucoid 1 (ORM1)

NM_000607.1

-0.947

3.99e-11

103021

Hydroxysteroid (17-beta) dehydrogenase 13 (HSD17B13)

NM_178135.2

-0.869

6.10e-11

201488

201488

 

0.462

1.08e-10

100575

17beta-estradiol dehydrogenase (HSD17B4)

NM_214306.1

0.452

1.24e-10

100723

Aspartate aminotransferase (GOT2)

NM_213928.1

0.493

3.71e-10

103194

Alpha-1 acid glycoprotein (AGP)

XM_585370.2

-0.932

4.52e-10

202082

Family with sequence similarity 10. member A4 (FAM10A4)

NR_002183.1

0.424

6.45e-10

100724

Phytanoyl-CoA hydroxylase (PHYH)

NM_006214.3

0.518

8.69e-10

210077

Cytochrome P450 2C49 (CYP2C49)

NM_214420.1

0.872

9.95e-10

101277

Estrogen sulfotransferase (STE)

NM_213992.1

0.557

1.45e-09

216031

Insulin-like-growth factor 2 (IGF2)

NM_213883.1

-0.687

1.88e-09

210204

Similar to HLA class I histocompatibility antigen, A-11 alpha chain precursor (LOC642049)

XM_936199.1

-0.591

1.88e-09

103031

Type I iodothyronine deiodinase (DIO1)

NM_001001627.1

0.499

2.85e-09

210252

Sarcosine dehydrogenase (SARDH)

NM_007101.2

-0.273

3.55e-09

102976

Similar to UDP-glucuronosyltransferase 2B15 precursor (UDPGT) (HLUG4) (LOC653180)

XM_931558.1

0.623

4.69e-09

201274

Sorbitol dehydrogenase (SORD). mRNA

NM_003104.3

0.523

5.70e-09

103801

Similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) (LOC650043)

XM_939131.1

0.452

1.83e-08

204461

Glycine-N-acyltransferase (GLYAT). nuclear gene encoding mitochondrial protein

NM_005838.2

0.370

2.47e-08

102538

102538

 

0.746

2.65e-08

204863

Hydroxysteroid (17-beta) dehydrogenase 13 (HSD17B13)

NM_178135.2

-0.630

3.89e-08

101843

Abhydrolase domain containing 3 (ABHD3)

NM_138340.3

0.370

9.87e-08

215880

Transcription elongation factor B (SIII). polypeptide 3 (110 kDa. elongin A) (TCEB3)

NM_003198.1

-0.612

9.87e-08

200322

Taxilin beta (TXLNB)

NM_153235.2

0.385

9.87e-08

210206

Metallothionein (MT1A)

NM_001001266.1

-0.536

1.25e-07

201503

Carboxylesterase (CES3)

NM_214246.1

0.472

1.44e-07

202070

202070

 

0.485

1.57e-07

102106

102106

 

0.335

1.86e-07

206300

Protein tyrosine phosphatase type IVA. member 1 (PTP4A1)

NM_003463.3

0.337

2.01e-07

103047

Similar to mouse 2310016A09Rik gene (LOC134147)

NM_138809.3

0.456

2.01e-07

204653

FKBP1A-like (LOC654323)

NM_001038000.1

0.256

2.06e-07

103327

UDP glucuronosyltransferase 1 family, polypeptide A5 (UGT1A5)

NM_019078.1

0.264

2.42e-07

102469

Chromosome 1 open reading frame 128 (C1orf128)

NM_020362.2

0.190

2.42e-07

201919

FKBP1A-like (LOC654323)

NM_001038000.1

0.303

2.53e-07

103349

Kininogen 1 (KNG1)

NM_000893.2

0.428

3.03e-07

103940

UDP glucuronosyltransferase 1 family, polypeptide A5 (UGT1A5)

NM_019078.1

0.191

4.03e-07

204455

Ornithine carbamoyltransferase (OTC)

NM_000531.3

0.357

4.61e-07

212598

L1 cell adhesion molecule (L1CAM)

NM_024003.1

-0.167

4.72e-07

207639

207639

 

0.383

4.83e-07

200534

200534

 

0.388

4.89e-07

102183

Protein tyrosine phosphatase type IVA. member 1 (PTP4A1)

NM_003463.3

0.360

5.72e-07

206424

Similar to transcription elongation factor B polypeptide 3 binding protein 1 isoform 1 (LOC533427)

XM_612827.2

0.265

6.41e-07

103306

Tryptophan 2.3-dioxygenase (TDO2)

NM_005651.1

0.443

6.41e-07

104125

Sorbitol dehydrogenase (SORD)

NM_003104.3

0.428

7.73e-07

102709

102709

 

0.444

7.76e-07

100472

S-adenosylhomocysteine hydrolase (AHCY)

NM_001011727.1

0.321

8.64e-07

206129

206129

 

-0.484

8.86e-07

102624

Ornithine carbamoyltransferase (OTC)

NM_000531.3

0.393

8.86e-07

213735

Metallothionein (MT1A)

NM_001001266.1

0.422

1.01e-06

102836

Carboxylesterase (CES3)

NM_214246.1

0.563

1.10e-06

201162

FKBP1A-like (LOC654323)

NM_001038000.1

0.268

1.42e-06

201961

201961

 

0.293

1.42e-06

216074

Metallothionein (MT1A)

NM_001001266.1

-0.772

1.64e-06

207278

207278

 

0.282

1.67e-06

101716

101716

 

0.328

1.75e-06

204421

Meiosis-specific nuclear structural 1 (MNS1)

NM_018365.1

0.364

1.99e-06

103156

103156

 

0.333

2.05e-06

103376

Hydroxysteroid (17-beta) dehydrogenase 13 (HSD17B13)

NM_178135.2

-0.497

2.38e-06

100064

Similar to UDP-galactoseN-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase (LOC645551)

XM_928571.1

0.159

2.43e-06

204950

Abhydrolase domain containing 3 (ABHD3)

NM_138340.3

0.236

2.43e-06

204048

Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) (ST13)

NM_003932.3

0.379

2.74e-06

204867

204867

 

0.308

2.95e-06

207963

207963

 

0.254

3.08e-06

200952

200952

 

0.236

3.08e-06

103294

Similar to Mob4B protein (MGC124888)

NM_001033891.1

0.369

3.79e-06

208427

RAR-related orphan receptor A (RORA)

NM_134262.1

0.246

4.25e-06

208058

FKBP1A-like (LOC654323)

NM_001038000.1

0.247

4.48e-06

205360

FLJ20105 protein (FLJ20105)

NM_017669.2

0.278

4.73e-06

207838

3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria) (HMGCL)

NM_000191.2

0.156

4.78e-06

101413

Replication protein A3. 14 kDa (RPA3)

NM_002947.3

0.253

5.25e-06

103180

T-complex 1 (TCP1)

NM_001008897.1

0.310

5.69e-06

202298

202298

 

0.262

5.73e-06

100384

Alpha-methylacyl-CoA racemase (AMACR)

NM_014324.4

0.394

6.68e-06

103434

Acyl-Coenzyme A oxidase 1, palmitoyl (ACOX1)

NM_004035.5

0.368

7.11e-06

202477

Hypothetical LOC505518 (LOC505518)

XM_581816.2

0.240

7.42e-06

102858

102858

 

0.587

7.52e-06

103058

103058

 

0.381

7.67e-06

211612

Gamma-aminobutyric acid (GABA) A receptor. alpha 3 (GABRA3)

NM_000808.2

-0.135

8.97e-06

201347

HRAS-like suppressor 3 (HRASLS3)

NM_007069.1

0.352

8.97e-06

102840

Sorbitol dehydrogenase (SORD)

NM_003104.3

0.270

8.97e-06

201105

COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) (COPS2)

NM_004236.1

0.242

9.06e-06

201848

Kinesin family member C1 (KIFC1)

NM_002263.2

0.274

9.06e-06

  1. Gene expression profiles were identified in Limma using empirical Bayes moderated t-statistics. Fold change and statistical significance is shown (FDR-adjusted p-values). The clone names refer to hits to pig, human, mouse or bovine sequences. Some genes are represented by several different clones on the array and may therefore show up more than once in the table, while others have no hits to the abovementioned species.
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BMC Veterinary Research

ISSN: 1746-6148

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