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Table 2 Genotype, breed distribution with inoculation details and incubation periods of BSE-negative sheep

From: Pruritus is a common feature in sheep infected with the BSE agent

 

Genotype

Breed

n

Oral dose (at age)

IP

Unchallenged (controls)

ARQ/ARQ

Romney

3

None

15, 21, 34

  

Suffolk

2

None

3, 15

 

ARQ/ARR

Romney

4

None

10, 21, 33, 45

 

ARR/ARR

Romney

4

None

9, 21, 33, 45

  

Suffolk

3

None

9, 34, 45

 

TOTAL

 

16

  

Challenged

ARQ/ARQ

Romney

5

5 g (6 months)

12 (1.22)

  

Suffolk

7

5 g (4 months)

9 (2.4)

  

Suffolk

1

0.5 g (6 months)

38

 

ARQ/ARR

Romney

17

5 g (6 months)

41 (6.7)

  

Romney

1

0.05 g (6 months)

50

  

Suffolk

13

5 g (4 months)

32 (6.1)

 

ARR/ARR

Romney

17

5 g (6 months)

42 (7.3)

  

Suffolk

15

5 g (4 months)

29 (3.4)

 

TOTAL

 

76

  
  1. IP = Incubation period in months (always rounded down), defined as time period from inoculation to cull and – for unchallenged animals in the oral BSE pathogenesis study – from test group exposure and cull. The mean incubation period with the standard error in parentheses is given if the numbers exceed four.