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Table 1 Genotype, breed distribution with inoculation details and incubation periods of confirmed BSE cases

From: Pruritus is a common feature in sheep infected with the BSE agent

Genotype

Breed

Dose (at age)

n

IP

AHQ/AHQ

Cheviot

5 g orally (4–9 months)

4

17, 17, 18, 18

ARQ/ARQ

Poll

5 g orally (6 months)

2

22, 29

 

Dorset

0.5 g orally (6 months)

1

25

 

Romney

5 g orally (4–7 months)

17

29 (2.1)

  

0.5 g orally (6 months)

2

23, 24

  

"Natural infection" (experimental flock)

1

24

 

Suffolk

5 g orally (4–8 months)

14

24 (0.9)

  

0.5 g orally (6 months)

1

25

  

"Natural infection" (experimental flock)

1

21

  

1 ml intracerebrally (8 months)

2

17, 18

VRQ/VRQ

Cheviot

5 g orally (4 months)

2

51, 54

  1. IP = Incubation period in months (always rounded down), defined as time period from inoculation (birth for naturally infected animals) to cull. The mean incubation period with the standard error in parentheses is given if the numbers exceed four. Excluded are the scheduled culls (seven Romney, four Suffolk sheep) in the oral pathogenesis studies (e.g. the pre-clinical cases).