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Table 3 AgNORs mean counts in canine MCTs: correlations with multiple pathologic variables

From: CD117 immunoexpression in canine mast cell tumours: correlations with pathological variables and proliferation markers

Pathological variables

AgNORs mean counts

(p value)

 

Median

min.

max.

IR

 

Histological grade

     

I

1.3

1.1

2.3

0.4

 

II

1.5

1.1

2.9

0.5

p < 0.001

III

2.4

1.2

4.2

1.6

 

Necrosis

     

No

1.4

1.1

3.8

0.5

p < 0.001

yes

1.9

1.2

4.2

1.3

 

Growth pattern

     

well circumscribed

1.3

1.2

4.2

0.6

P = 0.245

invasive

1.6

1.1

3.8

0.7

(NS)

Ulceration

     

no

1.4

1.1

4.2

0.5

p < 0.001

yes

1.8

1,2

3.8

1.3

 

Mitoses (per high power field)

     

0

1.4

1.1

2.7

0.4

 

1

1.6

1.2

2.9

0.4

p < 0.001

2

2.3

1.3

3.5

1.3

 

≥ 3

2.6

1.8

4.2

1.4

 

CD117 staining

     

membrane-associated

1.3

1.1

2.3

0.4

 

cytoplasmic focal

1.9

1.1

4.2

1.2

p < 0,001

cytoplasmic diffuse

1.6

1.2

3.4

1.3

 
  1. IR – interquartile range, NS – non-significant.