Pathological variables | AgNORs mean counts | (p value) | |||
---|---|---|---|---|---|
Median | min. | max. | IR | ||
Histological grade | |||||
I | 1.3 | 1.1 | 2.3 | 0.4 | |
II | 1.5 | 1.1 | 2.9 | 0.5 | p < 0.001 |
III | 2.4 | 1.2 | 4.2 | 1.6 | |
Necrosis | |||||
No | 1.4 | 1.1 | 3.8 | 0.5 | p < 0.001 |
yes | 1.9 | 1.2 | 4.2 | 1.3 | |
Growth pattern | |||||
well circumscribed | 1.3 | 1.2 | 4.2 | 0.6 | P = 0.245 |
invasive | 1.6 | 1.1 | 3.8 | 0.7 | (NS) |
Ulceration | |||||
no | 1.4 | 1.1 | 4.2 | 0.5 | p < 0.001 |
yes | 1.8 | 1,2 | 3.8 | 1.3 | |
Mitoses (per high power field) | |||||
0 | 1.4 | 1.1 | 2.7 | 0.4 | |
1 | 1.6 | 1.2 | 2.9 | 0.4 | p < 0.001 |
2 | 2.3 | 1.3 | 3.5 | 1.3 | |
≥ 3 | 2.6 | 1.8 | 4.2 | 1.4 | |
CD117 staining | |||||
membrane-associated | 1.3 | 1.1 | 2.3 | 0.4 | |
cytoplasmic focal | 1.9 | 1.1 | 4.2 | 1.2 | p < 0,001 |
cytoplasmic diffuse | 1.6 | 1.2 | 3.4 | 1.3 |