Figure 4

Daily body weight, food and water intake. The percentage deviation (delta) from baseline of body weight, and food and water intake is presented. Symbols represent the mean values from 8 animals, with bars indicating ± SEM. Corresponding control experiments in which animals received anesthesia and injections only are depicted as black horizontal lines with grey columns representing ± SEM. Asterisks indicate statistical significance (paired Student's t test with Bonferroni correction) at P ≤ 0.016. Note the reduction in body weight for three days and the decrease in food consumption for two days after laparotomy without pain treatment.