| Â |
scrapie positive in CNS
|
scrapie negative in CNS
|
|---|
| Â | WB | IHC | WB | IHC |
all genotypes
| 51/61 | 53/61 | 1/7 | 1/7 |
per genotype
| Â | Â | Â | Â |
ARQ/ARQ | 5/7 | 6/7 | 0/1 | 0/1 |
ARQ/ARR | none | none | 0/2 | 0/2 |
VRQ/VRQ | 6/6 | 6/6 | none | none |
ARQ/VRQ | 32/32 | 32/32 | 1†/2 | 1†/2 |
ARH/VRQ | 7/7 | 7/7 | none | none |
ARR/VRQ‡ | 1/9 | 2/9 | 0/2 | 0/2 |
- * Sources of animals were own flocks, clinical suspects, and slaughtered or fallen stock animals aging >18 m collected under EU surveillance program for small ruminants (see Methods section and for individual data Table in "additional file 1"). Figures indicate the number of positives/total number of animals analyzed. The analyses on central nervous system (CNS) were performed by Prionics Check and IHC, and concerned obex tissue analysis.
- †Animal aging 65 m, found dead from minimal scrapieincidence pressure flock.
- ‡ There were two samples (RLN65 and RLN67) which in three WB tests yielded once a weakly positive result, and twice (including after a concentration treatment) a negative result. In IHC, RLN65 was weakly positive, RLN 67 negative.
