Local cytokine transcription in naïve and previously infected sheep and lambs following challenge with Teladorsagia circumcincta

Table 1 Design of T. circumcincta infection experiments

Experiment	Age	Breed	Group	Trickle infection^a	Kill day following challenge^b
Experiment	Age	Breed	Group	Trickle infection^a	0	2	5	10	21
2	Yearling	Dorset × Suffolk	Naive	-	-	-	6^c	6^c	6^c
2	Yearling	Dorset × Suffolk	Previously Infected	+	-	-	6^c	6^c	-
4	Yearling	Scottish Blackface × Bluefaced Leicester	Naive	-	6	6	-	-	-
4	Yearling	Scottish Blackface × Bluefaced Leicester	Previously Infected	+	6	6	-	-	-
6	5 months	Dorset × Suffolk	Naive	-	4	-	6^c	6^c	6^c
6	5 months	Dorset × Suffolk	Previously Infected	+	4	-	6^c	6^c	6^c

^a2000 T. circumcincta L3 administered three times per week for 8 weeks.
^bQuoted figure is the number of animals in the group killed on the corresponding day following challenge.
^cCommon gastric lymph duct cannulated 4–7 days prior to challenge infection (day 0).

ISSN: 1746-6148