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Table 1 Correlation between the three antibody stains with the clinic and pathologic factors of the female dogs

From: Expression of glutathione, glutathione peroxidase and glutathione S-transferase pi in canine mammary tumors

Clinical and pathologic factors

Number of bitches

GSH

GSTpi

GSH-Px

Age

    

  ≥ 10 years

16 (53.3%)

185.3 ± 6.532

202.8 ± 2.537

194.4 ± 3.838

  < 10 years

14 (46.7%)

196.9 ± 6.170

206.5 ± 1.842

202.3 ± 2.936

  P

 

> 0.05

> 0.05

> 0.05

Time course

    

  Until 6 months

13 (50%)

196.5 ± 21.82

204.6 ± 6.172

202.9 ± 13.81

  Between 6 and 18 months

7 (27%)

182.3 ± 31.20

205.5 ± 9.397

192.5 ± 13.55

  More than 18 months

6 (23%)

180.0 ± 24.07

202.5 ± 14.49

190.8 ± 14.18

  P

 

> 0.05#

> 0.05#

> 0.05#

Histological type

    

  Malignant tumors

26 (87%)

189.9 ± 4.829

204.0 ± 1.757

198.3 ± 2.869

  Benign

4 (13%)

196.3 ± 15.69

209.3 ± 3.860

203.5 ± 4.173

  P

 

> 0.05

> 0.05

> 0.05

Clinical staging

    

  I

11 (37%)

202.3 ± 15.36

204.7 ± 5.746

199.4 ± 11.83

  II

4 (13%)

190.0 ± 45.03

208.0 ± 4.243

198.3 ± 19.57

  III

10 (33%)

183.3 ± 24.50

202.2 ±12.75

196.4 ± 13.09

  IV

5 (17%)

180.6 ± 21.13

206.0 ± 8.689

198.4 ± 18.94

  P

 

> 0.05#

> 0.05#

> 0.05#

Number of nodules

    

  Multiples

9 (30%)

177.9 ± 7.181

204.6 ± 2.844

200.8 ± 5.112

  Single

21 (70%)

196.2 ± 5.314

204.5 ± 2.001

197.4 ± 3.044

  P

 

> 0.05

> 0.05

> 0.05

Tumor ulcerated

    

  Ulceration

10 (34%)

180.8 ± 22.75

203.5 ± 13.53

205.0 ± 9.129

  Necrosis

2 (7%)

162.0 ± 55.15

204.9 ± 5.557

189.5 ± 6.364

  Absent

17 (59%)

199.4 ± 19.52

206.0 ± 8.485

195.2 ± 15.34

  P

 

0.03* #

> 0.05#

> 0.05#

Tumor vascularization

    

  Abundant

15 (50%)

184.1 ± 7.164

205.7 ± 2.080

197.9 ± 3.349

  Moderate

15 (50%)

197.3 ± 5.374

203.3 ± 2.499

198.2 ± 3.914

  P

 

> 0.05

> 0.05

> 0.05

Censure

    

  Death

8 (26.7%)

165.5 ± 8.592

204.1 ± 1.869

203.0 ± 3.937

  Living

22 (73,3%)

199.9 ± 3.921

205.9 ± 1.191

196.3 ± 3.099

  P

 

0.0003*

> 0.05

> 0.05

Metastasis

    

  Yes

8 (26.7%)

165.5 ± 8.592

204.1 ± 1.869

203.0 ± 3.937

  No

22 (73.3%)

199.9 ± 3.921

205.9 ± 1.191

196.3 ± 3.099

  P

 

0.0003*

> 0.05

> 0.05

  1. *Significant value to Student’s t test # ANOVA test.