Figure 4From: A recombinant chimera comprising the R1 and R2 repeat regions of M. hyopneumoniae P97 and the N-terminal region of A. pleuropneumoniaeApxIII elicits immune responsesCytokine profiles of splenocytes obtained from immunized mice. Mice were primed with Ap97, ApxN, or P97C vaccines. Splenocytes were isolated from each mouse and then re-stimulated with Ap97, ApxN, or P97C dissolved in PBS. At the end of re-stimulation, cell culture supernatants were analyzed for IFN-γ (A) and IL-4 (B). Data represent the mean ± SD (n = 4). *P < 0.05 and **P < 0.01, significantly different from the corresponding PBS-treated controls (paired t-test).Back to article page