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Table 4 Groups of piglets with different injections at different time points 1

From: Anti-idiotypic antibodies reduce efficacy of the attenuated vaccine against highly pathogenic PRRSV challenge

Time points2

Groups of piglets received injections1

 

1

2

3

4

5

6

0

Mab2-5G2

aAb2s

7H12

normal swine IgG

PBS

PBS

143

CH-1R

CH-1R

CH-1R

CH-1R

PBS

PBS

28

CH-1R

CH-1R

CH-1R

CH-1R

PBS

PBS

424

HP-PRRSV

HP-PRRSV

HP-PRRSV

HP-PRRSV

HP-PRRSV

PBS

  1. 1The amount of IgG each piglet received was 100 μg/kg of body weight and PBS was 2 mls via intramuscularly (i.m.) injection.
  2. 2The numbers were the days post injection (DPI). 42 DPI was also the 0 days post challenge (DPC).
  3. 3On 14 DPI, the piglets received CH-1R, the attenuated PRRSV vaccine and generated from CH-1a, a North American type strain isolated from China (GenBank no. EU807840) [24] i.m. on the left side of the neck at 2 doses/piglet diluted in 2 ml of PBS.
  4. 4On 42 DPI, the piglets were challenged with HP-PRRSV HuN4 strain at 3 × 105 TCID50/piglet and also considered as 0 days post challenge (DPC).