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Table 4 MIC distribution in methicillin-resistant S. aureus isolates from bovines

From: Epidemiology and molecular characterization of methicillin-resistant Staphylococcus aureusnasal carriage isolates from bovines

Antimicrobials

% of isolates with MIC (mg/l) of

% R

 

≤0.016

0.03

0.06

0.12

0.25

0.5

1

2

4

8

16

32

64

128

256

512

 

CHL

        

4.9

46.9

35.8

2.5

8.6

1.2

  

12.3

CIP

    

18.5

27.2

9.9

2.5

2.5

11.1

28.4

     

16.0

CLI

   

12.3

1.2

1.2

1.2

0.0

0.0

84.0

      

86.4

ERY

    

3.7

7.4

2.5

0.0

2.5

2.5

81.5

     

86.4

FOX

     

0.0

0.0

0.0

0.0

3.7

18.5

77.8

    

100.0

FUS

     

72.8

12.3

2.5

9.9

2.5

      

27.2

GEN

      

22.2

1.2

3.7

7.4

21.0

44.4

    

76.5

KAN

        

16.0

3.7

2.5

2.5

9.9

65.4

  

80.2

LZD

      

23.5

75.3

1.2

0.0

      

0.0

MUP

     

86.4

3.7

3.7

0.0

0.0

0.0

0.0

0.0

0.0

6.2

 

9.9

PEN

   

0.0

0.0

0.0

1.2

8.6

90.1

       

100.0

RIF

86.4

1.2

0.0

1.2

0.0

1.2

9.9

         

12.3

SMX

            

70.4

3.7

11.1

14.8

25.9

STR

        

14.8

22.2

4.9

9.9

48.1

   

58.0

SYN

     

32.1

44.4

8.6

8.6

6.2

      

23.5

TET

     

2.5

1.2

0.0

0.0

0.0

1.2

95.1

    

96.3

TIA

     

75.3

7.4

0.0

0.0

17.3

      

17.3

TMP

       

4.9

3.7

1.2

0.0

1.2

88.9

   

95.1

VAN

      

87.7

12.3

0.0

0.0

0.0

     

0.0

  1. CHL, chloramphenicol; CIP, ciprofloxacin; CLI, clindamycin; ERY, erythromycin; FOX, cefoxitin FUS, fusidic acid; GEN, gentamicin; KAN, kanamycin; LZD, linezolid; MIC, minimal inhibitory concentration; MUP, mupirocin; PEN, penicillin; R, resistance; RIF, rifampicin; SMX, sulfamethoxazole; STR, streptomycin; SYN, quinupristin/dalfopristin; TET, tetracyclin; TIA, tiamulin; TMP, trimethoprim; VAN,vancomycin.
  2. Empty boxes indicate the concentration values that were not tested. Values in grey boxes indicate MIC higher than the concentration tested.
  3. The bold lines indicate epidemiological cut-off values for S. aureus. MIC values were interpreted using the EUCAST clinical breakpoints/epidemiological cut-offs [1].