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Table 1 Comparison of HPC marker expression across species

From: Hepatic progenitor cells in canine and feline medicine: potential for regenerative strategies

Marker

Mouse

Rat

Cat

Dog

Human

A6

[3, 50]

    

ABCG2/BCRP1

[47]

[47]

 

[7]

[7, 48]

AFP

 

[47, 51, 52]

 

[53]

[48, 54–56]

Alb

[57]

   

[54, 55, 58]

Dlk/Pref-1

[59]

[47]

   

c-kit

 

[60]

  

[48, 56]

CD24

[50]

    

CD29

 

[51]

 

[53]

[54]

CD34

 

[60]

   

CD44

[49]

[51]

 

[53]

[48, 54, 55]

CD45

 

[60]

   

CD73

    

[54]

CD90

 

[52, 60]

  

[54]

CD133/PROM1

[49, 57, 59, 61]

[51]

 

[53]

[48]

CLDN3

    

[55]

chrom-A

    

[32, 33]

EpCAM

[50, 57, 59]

[45, 51]

  

[55, 62]

FN14

[59]

[51]

 

[53]

 

GPC3

 

[52]

   

Hedgehog proteins

   

Schotanus (unpublished data)

[55]

HNF4α

 

[45]

 

[53]

 

ICAM1

    

[55]

K7

[36, 57]

[32, 63]

[31]

[6, 7, 53]

[6, 7, 25, 32, 33, 48, 64, 65]

K8

    

[33, 54]

K18

    

[33, 54]

K19

[3, 37, 57, 59]

[32, 45, 51, 52, 63, 66]

 

[6, 53]

[6, 25, 32, 33, 48, 55, 56, 58, 64, 67]

Lgr5

[49]

    

MPK

 

[47]

   

NCAM

    

[32, 48, 55]

NES

    

[54]

Nope

[50]

    

OPN

[37]

  

[53]

 

OV6

 

[32, 45, 66]

  

[32, 33]

Sca1

[59]

    

SOX9

[36, 37, 49, 59, 61]

  

[53]

 

vimentin

    

[54]

  1. References are indicated per marker per species. Expression was measured at mRNA and/or protein level and was reported for adult liver.
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BMC Veterinary Research

ISSN: 1746-6148

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